
HELIX
Oncology Intelligence Platform
Making every oncologist as effective as the best oncologist. An AI-powered platform that transforms fragmented cancer care into a continuously-learning intelligence system spanning diagnostics, treatment matching, and clinical coordination.
Fragmented Cancer Care Kills
Cancer patients navigate a broken system where critical information falls through the cracks between specialists, diagnostics, and treatments.
The Information Gap
The average cancer patient sees 5-12 specialists who rarely communicate with each other. Critical treatment decisions are made with incomplete data. Patients retain only 20% of what's said during appointments while cognitively overwhelmed by their diagnosis.
Meanwhile, thousands of clinical trials run at any given time, yet fewer than 5% of eligible patients ever enroll. The gap isn't willingness - it's information and logistics.
The Billionaire vs. Everyone Else
GitLab CEO Sid Sijbrandij assembled a team of computational biologists, ran continuous diagnostics, and orchestrated personalized therapies for his cancer. HELIX productizes this approach for every oncologist and every patient.

Oncology Intelligence, Phased
HELIX builds the intelligence layer that connects the entire cancer care journey - from diagnosis through treatment, one validated phase at a time.
Clinical Intelligence Layer
Ambient capture of every appointment, automatic structuring into a patient knowledge graph, AI-powered clinical trial matching against global registries, and care coordination summaries tailored per specialist domain. Ships in 6 months.
Multi-Omic Diagnostic Fusion
Integration of genomic, transcriptomic, proteomic, liquid biopsy, bloodwork, and wearable data into a continuously-updated tumor model for 2-3 cancer types (breast, colorectal). Predictive alerts surface recurrence months before imaging.
Treatment Response Engine
AI ranks treatment candidates by predicted efficacy for each patient's current tumor state. Drug repurposing engine matches 20,000+ approved drugs against multi-omic tumor profiles via ChEMBL, DrugBank, OncoKB, and DGIdb databases.
Personalized Therapy Coordination
Orchestration layer for personalized mRNA neoantigen vaccines, multi-target cell therapies, and AI-designed small molecules. Coordinates manufacturing logistics, regulatory pathways, and outcome tracking.

A $100B+ Addressable Market
Oncology is the single largest healthcare market on Earth, and precision medicine is reshaping it.

Why HELIX Wins
Full-Journey Intelligence
Tempus sells data to providers. Flatiron sells to pharma. Foundation Medicine does genomic profiling. HELIX is the first platform connecting diagnosis through treatment as continuous intelligence.
Physician-First Design
Built as decision support that makes oncologists heroes, not algorithm executors. Human-in-the-loop for every recommendation.
Data Flywheel
After 10,000 concentrated patients in 2-3 cancer types, prediction accuracy exceeds any individual oncologist's pattern recognition. This dataset is unreplicable.
UAE Beachhead Strategy
Launch in UAE with favorable regulatory environment, cash-pay patients, and government alignment with medical tourism innovation.
Federated Learning Architecture
Privacy-preserving model training across clinical sites without sharing raw patient data. Enables multi-institutional collaboration no competitor can replicate.
IP Protection
4-patent portfolio covering adaptive oncology knowledge graphs, multi-modal diagnostic fusion, genomic-aware trial matching, and federated oncology networks.

Path to Market
From clinical workflow tool to the world's most powerful oncology intelligence platform.
CORE: Clinical Intelligence
Ship ambient transcription + structured extraction + trial matching. Deploy at 3 UAE oncology centers. Validate physician adoption metrics. Secure 2-3 exclusive data partnerships.
SIGNAL: Diagnostic Fusion
Integrate liquid biopsy (ctDNA), whole genome + transcriptome sequencing, and proteomics into tumor model. Focus on breast and colorectal cancers. Expand to 10+ clinical sites.
PREDICT: Treatment Intelligence
Launch treatment response prediction and drug repurposing engine. FDA pre-submission for clinical decision support. Target 50+ clinical sites and 10,000 patient dataset.
DESIGN: Therapy Orchestration
Coordinate personalized mRNA neoantigen vaccines and multi-target cell therapies. Full global platform expansion contingent on Phase 3 validation.

From Diagnosis to Survivorship
Community Oncology Augmentation
Community oncologists access the same intelligence as major cancer centers. Knowledge graph surfaces relevant clinical evidence and trials without manual research.
Multi-Disciplinary Tumor Board
AI generates comprehensive case summaries before tumor board review. Surfaces discordant recommendations and evidence gaps automatically.
Clinical Trial Enrollment
Continuous matching against 5,000+ active oncology trials. Logistics coordination handles pre-screening, site identification, and enrollment support.
Recurrence Monitoring
Post-treatment patients receive continuous multi-omic surveillance. Predictive alerts catch recurrence months before standard imaging intervals.

Part of the Moonshot Rodeo Healthcare Suite
SYNAPSE Integration
Cancer patients on complex regimens receive drug interaction monitoring. Oncology care meets polypharmacy safety.
ORPHEON Cross-Platform
Rare cancer patients benefit from quantum drug repurposing. Overlapping patient populations across healthcare moonshots.
QCortex Backend
Shared AI/ML infrastructure and federated learning capabilities across portfolio. 80%+ resource utilization through workload pooling.
